Evidence-based information & thrombosis awareness
About IMHA Toolkit
Why This Site Exists
IMHA Toolkit was created to make information about Immune-Mediated Haemolytic Anaemia (IMHA) easier to access, understand and apply.
IMHA is a serious and potentially life-threatening disease seen most commonly in dogs but also recognised in cats and horses. The depth of evidence differs substantially between species. Important information is spread across consensus statements, peer-reviewed papers, pharmacology references and specialist resources, which can make reliable material difficult to locate quickly when it is needed.
The aim of IMHA Toolkit is to bring together key information, clinical references, educational resources and practical tools in one place. The site is intended to support understanding of IMHA, thrombotic risk, treatment approaches and patient monitoring, while encouraging readers to consult the original literature and seek appropriate professional advice.
The Story Behind IMHA Toolkit
The inspiration for this project was Luna.
Luna was a much-loved rescue dog who became seriously ill with Immune-Mediated Haemolytic Anaemia in 2025. During her treatment, her family spent countless hours researching the disease, reading veterinary literature and trying to understand the rapidly evolving evidence surrounding IMHA and its complications.
Although Luna initially responded well to treatment, she later suffered catastrophic thromboembolic disease and died unexpectedly.
In the months that followed, a detailed review of the veterinary literature reinforced how important thrombosis is in canine IMHA and how difficult it can be for owners—and sometimes clinicians—to navigate a large, scattered and uneven evidence base quickly.
IMHA Toolkit was created in Luna’s memory with the hope that bringing together educational resources, research findings and practical tools may help others facing the same diagnosis.
How Content Is Developed
Content published on IMHA Toolkit is compiled from published veterinary literature, with priority given to consensus statements, peer-reviewed studies and primary-source pharmacology or clinical research where available. Educational and secondary sources are used for context rather than as substitutes for stronger primary evidence.
Particular emphasis is placed on:
- The 2019 ACVIM consensus statements on diagnosis of IMHA in dogs and cats and treatment of canine IMHA
- Peer-reviewed veterinary research
- CURATIVE antithrombotic consensus guidance and species-specific thrombotic-risk evidence
- Species-specific veterinary pharmacology references and clinical studies
- Recent retrospective cohorts and prospective trials where available
References are linked to the original source or to the IMHA Toolkit Evidence Library wherever possible. When evidence is retrospective, uncontrolled, extrapolated from another disease or species, or based mainly on expert consensus, that limitation is stated in the page text.
Open the IMHA Toolkit Evidence Library →Editorial Oversight
IMHA Toolkit is independently researched, written and edited by John Tosh.
John is not a veterinary surgeon.
He is a UK-based science graduate, researcher, digital publisher and content creator. He studied Genetics at University College London and developed IMHA Toolkit following Luna’s illness and the extensive literature review that followed. His role is to locate, compare, organise and present information from published veterinary sources in a format that is accessible to veterinary professionals and animal owners.
The site does not claim to establish new clinical guidance or replace professional veterinary judgement. Its purpose is educational and informational.
⚠️ Important Notice
IMHA Toolkit does not provide veterinary advice.
Information contained on this website is provided for educational and informational purposes only and should not be used as a substitute for professional veterinary diagnosis, treatment or prescribing decisions.
Veterinary professionals must independently verify all drug dosages, treatment protocols, calculations and clinical recommendations before applying them to any patient.
Pet owners should always consult their veterinary surgeon regarding the diagnosis, treatment and management of any medical condition.
The site is reviewed and updated as new evidence becomes available, but veterinary knowledge changes over time. Readers should check the publication date, source and current formulary or consensus guidance before applying any clinical information.
In Memory of Luna
This website is dedicated to Luna, whose life inspired its creation. Her story reminds us that behind every clinical paper, treatment protocol and research statistic is a beloved companion and a family doing everything they can to help them.
"Good girl, Luna."Explore Resources
Use the educational dose-reference tools or review the consensus statements and peer-reviewed studies that underpin the site.